The Czech player found rhythm just in time to win nine consecutive games to finally secure her 90th career main draw victory on clay.
After the second round, Shanghai overtook Wuhan to lead the championship group on four points.
American Sara Hall, who sprinted to surpass world champion Ruth Chepngetich in the last meters, finished second in 2:22:01. Chepngetich from Kenya completed the race four seconds later.
Dongguan saw the national trio of Li Yueru, Yang Liwei and Huang Sijing depart to Inner Mongolia during the offseason.
Next up for Kvitova is Germany's Laura Segemund, who dispatched Spaniard Paula Badosa 7-5, 6-2 to advance. Enditem
Both male and female professional cyclists will compete in 60km and 30km individual races respectively, around Lake Ulan Suhai.
"Speed is her advantage. We hope she can improve her vision on the court and shooting ability," added the former head coach of China's women's junior national team. Enditem
Dongguan opened the first quarter on an 11-2 run, sparked by five straight points from Yang Shuyu.
The 31-year-old also became the first Chinese singles player since Li Na in 2012 to reach the fourth round at Roland-Garros.
HOHHOT, Oct. 5 (Xinhua) -- The Tour of Lake Ulan Suhai cycling race has been scheduled from October 12 to 14 in Urad Front Banner, Bayannur City, north China's Inner Mongolia Autonomous Region, the local sports bureau said on Monday.
"We know that Shanghai boasts a quick pace and three-pointer shooting ability. We had a great defense and restrained the opponents' character today," said Xinjiang coach Gao Fengjuan.